Use of Kiratatikta and Guduchi in Sickling

A clinico-pathological study of Sannipataja Pandu Roga and its comparative management with Kiratatikta Ghanavati and Guduchi Ghanavati W.S.R. to Sickle Cell Anaemia

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/01/039669

Enrollment

120

Registered

2022-01-21

Start date

Unknown

Completion date

Unknown

Last updated

2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: D571- Sickle-cell disease without crisis

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: i) Patients will be selected on the basis of sign and symptoms of sickle cell anaemia group:- 1. Anaemia 2. Jaundice 3. Bodyache (pain & crisis) 4. Abdominal colic 5. Palpitation 6. Hand foot syndrome 7. Loss of appetite 8. Sternal pain 9. Pyrexia 10. Hepatomegaly 11. Splenomegaly 12. Repeated blood transfusion 13. Repeated respiratory infections 14. Pain in Hip region ii) Hemoglobin more than 6gm/dl. iii) Age group between 5 Years to 50Years. As per the above sign and symptoms patients examination Performa will be prepared and patients will be selected for clinical trial.

Exclusion criteria

Exclusion criteria: 1. Patients who are suffering from pain and other symptoms other then Sickle cell anaemia will be excluded from the clinical trial. 2. The patients who are below 5 years and above 50 years. 3. Pregnancy and lactations 4. Severe illness like Tuberculosis, Cancer, Cirrhosis of liver, aplastic anaemia etc. also be excluded.

Design outcomes

Primary

Measure	Time frame
Laboratory Investigation will be assess:- 1. Haematological investigations (CBC, Vit.B12, Vit.D) 2. Biochemical investigations( LFT, KFT, Lipid profile) 3. Hb electrophoresis 4. Urine test (routine and microscopic along with bile salt and bile pigment) 5. Radiological investigations ( if required) 6. Invitro slide study Timepoint: 2 months	—

Secondary

Measure	Time frame
Laboratory Investigation will be assess:- 1. Haematological investigations (CBC, Vit.B12, Vit.D) 2. Biochemical investigations( LFT, KFT, Lipid profile) 3. Hb electrophoresis 4. Urine test (routine and microscopic along with bile salt and bile pigment) 5. Radiological investigations ( if required) 6. Invitro slide study Timepoint: at 15 days, 30 days, 45 days and 60 days.	—

Countries

India

Contacts

Public ContactDr Chandreshwar Prasad Sinha

Sambalpur University, Jyoti Vihar, Burla, Odisha

drpkpandanidan@rediffmail.com9437150643

Outcome results