Health Condition 1: H357- Separation of retinal layers
Conditions
Interventions
Intervention1: Intravitreal Ozurdex Implantation: Intravitreal Ozurdex Implantation
Single Dose
Follow up- Weekly for 2 weeks, 6 weeks, 12 weeks, 3 monthly thereafter till 1 year
Control Intervention1
Sponsors
Hyderabad Eye Research Foundation
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with non-resolving and recurrent CSCR with focal, multifocal, or diffuse leaks on FA 2. Eyes with focal leaks within 1000microns of the center of fovea in chronic CSCR 3. Best corrected vision score of 73 to 34 at test distance of 4 meters on ETDRS chart at recruitment (Snellen equivalent 20/40 to 20/200) 4. Decrease in vision primarily secondary to CSCR 5. Willing to sign informed consent form
Exclusion criteria
Exclusion criteria: 1. Laser or pharmacological treatment for CSCR in previous six months 2. Eyes with choroidal neovascularization demonstrated on OCTA/FA/ICGA 3. Fellow eye vision worse than 20/200 4. Aphakia 5. Patients with glaucoma.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Reappearance of disease % Requiring retreatment Changes in PED height Lens changes % Requiring medical/surgical treatment for glaucoma Timepoint: 3,6,9 and 12 months | — |
Primary
| Measure | Time frame |
|---|---|
| Complete resolution of SRF as determined on OCT The disappearance of intraretinal cystoid spaces Visual acuity change Change in contrast sensitivity Change in mfERG waveforms Change in intraocular pressure Timepoint: 6 and 12 weeks | — |
Countries
India
Contacts
Public ContactMohammed Hasibur Rahman
L V Prasad Eye Institute
Outcome results
None listed