Health Condition 1: H188- Other specified disorders of cornea
Conditions
Interventions
Intervention1: Topical Cyclosporin A (0.05%) Eye drop: 1 drop BD, topical for 6 months
Control Intervention1: Topical Tacrolimus (0.03%) eye ointment: rice grain sized amount, OD, topical for 6 months
Sponsors
Regional Institute of Ophthalmology Kolkata
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with Dry eye symptoms such as Discomfort, Fatigue and Gritty sensation 2. Schirmer’s Test 3. TBUT 4. OSDI score > 15 5. Presence of Punctate staining in the Fluorescence staining of the cornea, NEI score > 3
Exclusion criteria
Exclusion criteria: 1. Previous Eye Surgery 2. Use of ocular medication other than tear substitutes. 3. Contact lens wearer 4. Glaucoma patients 5. Pregnant or Lactating Mothers 6. Presence of any microbial infection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the improvement of OSDI score, schirmer I score, TBUT and NEI score in both groupTimepoint: 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the improvement the dry eye state of the symptomatic patients.Timepoint: 6 months;To assess the symptomatic improvement of dry eye disease patients with the above treatments.Timepoint: 6 months;To assess the visual outcome after the treatment.Timepoint: 6 months;To study prospectively the epidemiological scenario of dry eye in eastern India.Timepoint: 6 months | — |
Countries
India
Contacts
Public ContactAshis Majumdar
Purulia Government Medical College and Hospital
Outcome results
None listed