Comparitive study between two class of anti-hypertensives on intraoperative hemodynamics and surgical conditions during polypectomy surgery

A comparison of Effect of oral pre-medication with Clonidine and Metoprolol on intraoperative hemodynamics and surgical conditions during functional endoscopic sinus surgery

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/01/039572

Enrollment

Registered

2022-01-19

Start date

Unknown

Completion date

Unknown

Last updated

2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Tablet Clonidine 300 Î¼g: Clonidine is an Î±â??-adrenergic agonist medication used to treat high blood pressure, attention deficit hyperactivity disorder, drug withdrawal, menopausal fl

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients undergoing general anaesthesia 2. ASA Grading I, II

Exclusion criteria

Exclusion criteria: 1. ASA 3 and ASA 4 2. Age 60 years 3. History of hypertension 4. History of asthma 5. Patients already on beta blockers or clonidine 6. Contraindication to general anaesthesia

Design outcomes

Primary

Measure	Time frame
estimate the quality of the operative field and to grade according to the Average Category Scale (ACS) proposed by Fromm and Boezaart. Surgical field was graded as Good - ACS 0 or 1 Fair - ACS 2 or 3 Poor â??ACS 4 or 5 Timepoint: 3 hours	—

Secondary

Measure	Time frame
Blood loss intra operativelyTimepoint: 3 hours	—

Countries

India

Contacts

Public ContactSwadika N

Vinayaka Missions Kirupananda Variayar Medical College and Hospitals

shanushanmugasundaram@gmail.com8056603011

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026