COMPARISION OF ORIENTATION CHANGES IN OLD PATIENTS FOLLOWING GENERAL ANESTHESIA USING GASES ISOFLURANE VS DESFLURANE GAS

COMPARATIVE EVALUATION OF POST-OPERATIVE COGNITIVE DYSFUNCTION IN ELDERLY PATIENTS FOLLOWING GENERAL ANESTHESIA USING ISOFLURANE AND DESFLURANE

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/01/039540

Enrollment

Registered

2022-01-18

Start date

Unknown

Completion date

Unknown

Last updated

2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: DESFLURANE: DESFLURANE AS INHALATIONAL ANESTHETIC AGENT FOR 1-2 HRS OF SURGERY Control Intervention1: ISOFLURANE: ISOFLURANE AS INHALATIONAL ANESTHETIC AGENT FOR 1-2 HRS OF SURGERY

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1 AND 2 PATIENTS EXPECTED DURATION OF SURGERY 1-2 HOURS MODE OF ANAESTHESIA IS GENERAL ANAESTHESIA

Exclusion criteria

Exclusion criteria: PATIENTS UNABLE TO COMPREHEND THE REQUIRED COGNITIVE ASSESSMENT TESTS. HINDI MENTAL STATE EXAMINATION10 SCORE KNOWN CASES OF ANY PSYCHIATRIC ILLNESS. HISTORY OF CEREBROVASCULAR ACCIDENT. KNOWN DISORDER AFFECTING COGNITION. KNOWN HISTORY OF ALCOHOL/DRUG ABUSE.

Design outcomes

Primary

Measure	Time frame
INCIDENCE OF POCD ON POSTOPERATIVE DAY 1 AS ASSESSED BY HINDI MENTAL STATE EXAMINATION(HMSE) Timepoint: 1 day	—

Secondary

Measure	Time frame
CORELATION BETWEEN POCD WITH 1.AGE 2.DURATION OF EXPOSURE TO INHALATIONAL ANESTHESIA 3.LEVEL OF EDUCATION Timepoint: 1 day	—

Countries

India

Contacts

Public ContactUPASANA

MAULANA AZAD MEDICAL COLLEGE

drsukhi25@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026