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Comparison of effectiveness of two drugs namely dexmeditomidine and magnesium sulfate for pain relief in uterus removing surgery under spinal anaesthesia

Comparison of preoperative infusion of dexmeditomidine versus magnesium sulfate for post operative analgesia in total abdominal hysterectomy under subarachnoid block

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/01/039524
Enrollment
60
Registered
2022-01-18
Start date
Unknown
Completion date
Unknown
Last updated
2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Comparison of two drugs Dexmeditomidine and Magnesium sulfate: Single dose preoperative infusion of 0.5 mcg/kg Dexmeditomidine versus 30mg/Kg Magnesium sulfate intravenously for postope

Sponsors

DM Wayanad Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.American Society of Anesthesiologists physical status I or II 2.BMI less than 30 Kg/m2

Exclusion criteria

Exclusion criteria: 1. Conversion to GA during surgery 2. Bleeding disorders or Coagulopathy 3. Allergic to study drugs 4. Patients on chronic analgesic medications 5 Patients having respiratory or cardiovascular disease 6. Baseline heart less than 60 beats/minute 7. Patients on antiepileptics 8. Duration of surgery more than 2 hours

Design outcomes

Primary

MeasureTime frame
1. Sensory level after 5 minutes 2. Time to first request of analgesic (Duration of analgesia) 3. Numerical rating scale at 3, 6,12,24,48 hours post operatively Timepoint: 1. Sensory level after 5 minutes 2. Time to first request of analgesic (Duration of analgesia) 3. Numerical rating scale at 3, 6,12,24,48 hours post operatively—

Secondary

MeasureTime frame
Intraoperative Heart rate, Mean arterial pressure , respiratory rate and sedation scoreTimepoint: Heart rate, means arterial pressure, respiratory rate is recorded at 5minutes intervals. Patients sedation will be assessed using Ramsay sedation score 10 minutes, 30 minutes and hour after SAB—

Countries

India

Contacts

Public ContactArun Aravind

DM Wayanad Institute of Medical Sciences

drarunaravindcmc49@gmail.com09446864832

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026