Health Condition 1: C060- Malignant neoplasm of cheek mucosa
Conditions
Interventions
Intervention1: Peritumoral injection of methylene blue dye to identify the sentinel nodes.: After skin incision and raising of skin flaps as in a conventional neck dissection, dye will be injected per
Sponsors
Kidwai Memorial Institute of Oncology
Eligibility
Inclusion criteria
Inclusion criteria: Consecutive patients with biopsy proven, upfront operable SCC of the buccal mucosa, with no clinical or radiological evidence of cervical lymphadenopathy.
Exclusion criteria
Exclusion criteria: Patients who were under 18 years of age, oral cavity subsites other than buccal mucosa, with prior history of head and neck surgery, recurrent oral cancer or any form of neoadjuvant therapy, patients with palpable lymphadenopathy and those who did not consent to the procedure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pattern of lymph nodal spread in buccal mucosa SCC SLN identification rate with blue dye The accuracy (including the true positive and false negative rate) of blue dye in predicting the nodal status of the neck.Timepoint: 8 weeks (at study completion) | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of nodal metastases in clinically node negative SCC of the buccal mucosa Identification and correlation of tumor factors predictive of nodal involvement.Timepoint: 4 weeks | — |
Countries
India
Contacts
Public ContactJoseph Mathew
Kidwai Memorial Institute of Oncology
Outcome results
None listed