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Study to define interventions for improving antibiotic use in hospitals

Randomised control trial on impact of clinical pharmacist led interventions on antibiotic stewardship program in a tertiary care hospital in southern India.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/01/039502
Enrollment
150
Registered
2022-01-17
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: B968- Other specified bacterial agents as the cause of diseases classified elsewhere

Interventions

Intervention1: Clinical Pharmacist intervention: Check if a diagnosis has been documented at admission Check if antibiotic prescribed for the diagnosis are according to the recommendations of pediatri

Sponsors

Aster Medcity Kochi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All pediatric patients, 18 yrs old and less, admitted at Aster Medcity during the study period who were prescribed antibiotic/s

Exclusion criteria

Exclusion criteria: 1. Any patient more than 18yrs old 2. All children in whom antibiotics were given for procedural prophylaxis

Design outcomes

Primary

MeasureTime frame
Impact of additional clinical pharmacist intervention on appripriate and cost effective antibiotic useTimepoint: at discharge and 4 weeks after discharge

Secondary

MeasureTime frame
1. Assess rates of MRSA, MDR TB, MDR Typhoid, ESBL UTI, MDR Clostridium difficile, MDR BAL cultures, MDR fungal infections 2. Antibiotic prescribing according to standard guidelines (IAP DF/ BNFc) including IV to oral switch ââ?¬â?? prescribing errors ââ?¬â?? indication/dose/route of administration/duration/ 3. Time to review culture result ââ?¬â?? culture guided antibiotic selection 4. Defined daily dose (DDD)/1,000 patient-days of antibiotics used in pediatrics 5. Antimicrobial days of therapy (DOT) - Antimicrobial consumption for specific conditions [e.g., community-acquired pneumonia, VAP, MRSA bacteremia, ESBL UTI] 6. Antimicrobial-free days 7. Overall mass of various antimicrobials in grams being consumed by patients 8. Cost of therapy 9. Clinical outcomes ââ?¬â?? Length of hospital stay Cure / Mortality 10. Relapses / hospital readmission / need for follow up visits in the 1 moth following discharge Timepoint: At admission, 72 hr and 1 week after antibiotics are started aat discharge and at 1 month follow up

Countries

India

Contacts

Public ContactDr Jeeson C Unni

Aster Medcity, Kochi

drjeeson.unni@asterhospital.com9847245207

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026