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Comparison of Letrozole alone with Letrozole and HCG on pregnancy rates in PCOS women with anovulatory infertility : A randomised controlled trial

Comparison of Letrozole alone with Letrozole and HCG on pregnancy rate in pcos women with anovulatory infertility : A randomised controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/01/039450
Enrollment
75
Registered
2022-01-14
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N970- Female infertility associated withanovulation

Interventions

Intervention1: Letrozole and HCG Injection HCG five thousand IU im given when follicle diameter reached more than 18mm along with tab Letrozole: Injection HCG five thousand IU im given when follicl

Sponsors

Lady Hardinge Medical college
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Anovulatory Infertile PCOS women in age group 20 -35 years.

Exclusion criteria

Exclusion criteria: S.FSH levels > 10 IU/L Other associated causes of female infertilty such as tubal factor or male factor Women with history of ovarian surgery , ovarian tumor , pelvic adhesions or endometriosis.

Design outcomes

Primary

MeasureTime frame
Proportion of women with positive urinary pregnancy test in each group when they are overdue by 1 week from expected date of mensesTimepoint: when they are overdue by 1 week from expected date of menses

Secondary

MeasureTime frame
Proportion of women with USG documented live pregnancy in each group after two weeks overdue from expected date of menses. Comparison of mean duration of luteal phase in both groups. Comparison of D21 mean serum progesterone levels in both groups. Timepoint: Not applicable as it will depend on when the patient is getting periods

Countries

India

Contacts

Public ContactNeeraj

LHMC

drmanjupuri@gmail.com9654072706

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026