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Comparison of two different drugs as Adjuvants in spinal anesthesia for Abdominal Hysterectomy surgeries.

Comparison of the Postoperative Analgesia between Fentanyl and Dexmedetomidine as Adjuvants to Intrathecal Bupivacaine for Abdominal Hysterectomy Patients in a Tertiary Care Centre in Kerala

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/01/039437
Enrollment
50
Registered
2022-01-14
Start date
Unknown
Completion date
Unknown
Last updated
2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: INTRATHECAL BUPIVACAINE WITH DEXMEDETOMIDINE: 3ml 0.5% Bupivacaine with 10mcg DEXMEDETOMIDINE given in SAB. Duration of postoperative analgesia noted in total abdominal hysterectomy pat

Sponsors

PUSHPAGIRI INSTITUTE OF MEDICAL SCIENCES AND RESEARCH CENTRE
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: PATIENTS OF ASA STATUS 1 & 2

Exclusion criteria

Exclusion criteria: 1.PATIENT REFUSAL 2.PATIENT ON ALPHA BLOCKERS, BETA BLOCKERS DRUGS 3.PATIENT SENSITIVE OR ALLERGIC TO STUDY MEDICATIONS 4.PATIENTS OF ASA STATUS 3 & 4

Design outcomes

Primary

MeasureTime frame
TIME OF RESCUE ANALGESIA Timepoint: VAS SCORE ASSESSED AT 1hr 2hr 3hr 4hr 6hr 12hr 24hr RESCUE ANALGESIA GIVEN WHEN VAS SCORE MORE THAN 4 OR ON PATIENT REQUEST TIME IN MINUTES NOTED DURATION OF ANALGESIA NOTED

Secondary

MeasureTime frame
DURATION OF MOTOR BLOCKTimepoint: MODIFIED BROMAGE SCALE SCORE 0;DURATION OF SENSORY BLOCKTimepoint: GRADE 2 ON PIN PRICK;HEART RATETimepoint: 5,10,15,20,25 and 30min after injection and subsequently every 15 min.;SPO2Timepoint: 5,10,15,20,25 and 30min after injection and subsequently every 15 min.;SYSTOLIC AND DIASTOLIC BLOOD PRESSURETimepoint: 5,10,15,20,25 and 30min after injection and subsequently every 15 min.;TIME OF ONSET OF MOTOR BLOCKTimepoint: BY MODIFIED BROMAGE SCALE SCORE 3;TIME OF ONSET OF SENSORY BLOCKTimepoint: BY PIN PRICK METHOD GRADE 0 NO SENSATION FELT

Countries

India

Contacts

Public ContactVijitha Baby

Pushpagiri Institute of Medical Sciences and Research Centre Tiruvalla

mathewskthomas@yahoo.com7356879388

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026