Effect Of Dexmedetomidine An Analgesic Drug As An Additive In Errector Spinae Plane Block In Spine Surgery

Effect Of Dexmedetomidine As An Adjuvant In Erector Spinae Plane Block On Postoperative Analgesia In Thoracolumbar Spine Surgery With An Opioid Free Anaesthesia Technique: A Prospective Randomized Clinical Trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/01/039431

Enrollment

Registered

2022-01-14

Start date

Unknown

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M959- Acquired deformity of musculoskeletal system, unspecified

Interventions

Intervention1: DEXMEDETOMIDINE: ADDITION OF DEXMEDETOMIDINE 1MCG/KG IN ERECTOR SPINAE PLANE BLOCK AND COMPARISON OF POSTOPERATIVE PAIN FREE PERIOD Control Intervention1: ROPIVACAINE: ONLY ROPIVACAINE

Eligibility

Inclusion criteria

Inclusion criteria: 1) Age :18-65 years 2) Male/female 3) ASA 1 and 2 4) Patient posted for lower thoracic and upper lumber spine surgery (T8-L3) involving 2-4 intervertebral spaces. 5) Nontraumatic cases and Traumatic cases with no other skeletal trauma 6) Patient able to grade severity of pain.

Exclusion criteria

Exclusion criteria: 1) Preoperative pain score more than or equal to 5 2) BMI >35kg/m2 3) Pregnant or lactating woman 4) Patient with CAD/bradycardia/heart block/arrhythmias 5) Patient with hepatic/renal failure /CNS pathology 6) Patient with psychiatric disorder. 7) Patient not able to assess and tell severity of pain 8) Patients with allergies to any study medication. 9) Inability to position patient for block 10) ASIA A spine injury

Design outcomes

Primary

Measure	Time frame
To compare duration of pain free period postoperatively in patients receiving ESP block with ropivacaine and dexmedetomidine Vs ropivacaine alone.Timepoint: 1) postoperative pain scores at 0,2,4,6,8,12 and 24 hrs 2) rescue analgesic requirements during first 24 hour after surgery.	—

Secondary

Measure	Time frame
1. To compare postoperative pain scores at 0,2,4,6,8,12 and 24 hrs 2. To compare rescue analgesic requirements during first 24 hour after surgery. 3. To compare intraoperative qNOX values as a measure of intraoperative analgesia. 4. To compare intraoperative hemodynamic parameters (HR and MAP) 5. To compare patientsâ?? satisfaction regarding postoperative analgesia in patients receiving ESP block with ropivacaine and dexmedetomidine Vs ropivacaine alone . Timepoint: Post operative period at 0,2,4,8,12,24 hrs and intraoperative	—

Measure

Time frame

1. To compare postoperative pain scores at 0,2,4,6,8,12 and 24 hrs 2. To compare rescue analgesic requirements during first 24 hour after surgery. 3. To compare intraoperative qNOX values as a measure of intraoperative analgesia. 4. To compare intraoperative hemodynamic parameters (HR and MAP) 5. To compare patientsâ?? satisfaction regarding postoperative analgesia in patients receiving ESP block with ropivacaine and dexmedetomidine Vs ropivacaine alone . Timepoint: Post operative period at 0,2,4,8,12,24 hrs and intraoperative

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Countries

India

Contacts

Public ContactSWATI VERMA

PGIMER CHANDIGARH

nidhibp@gmail.com7087009525

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: May 1, 2026