Health Condition 1: K750- Abscess of liver
Conditions
Interventions
Intervention1: metronidazole: Tablet Metronidazole 800 mg TDS or injectable metronidazole 1 g iv 8 hourly for 10 days will be given to patients of liver abscess randomised into metronidazole group.
Co
Sponsors
Dr BSA Hospital
Eligibility
Inclusion criteria
Inclusion criteria: All consenting patients presenting to surgery opd/emergency in given duration of time with evidence of single liver abscess.
Exclusion criteria
Exclusion criteria: 1.USG evidence of presence of multiple liver abscesses. 2.Clinical signs and symptoms of intraperitoneal rupture of abscess. 3.Very sick patient requiring ICU admission 4.Age 60 years 5.Pregnant women 6.Patient with history of malignancy past or present
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the efficacy of Metronidazole vs Tinidazole vs Secnidazole in a triple arm randomised controlled trial study in patients of Amoebic Liver Abscess.The efficacy will be assessed by resolution of symptoms and signs like fever, abdominal pain, right hypochondrium tenderness and leucocytosis.Timepoint: At 1 month and 3 months from date of discharge | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.To compare the incidence of complications like intra peritoneal rupture, pleural effusion, atelectasis 2.To report drug related side effect like nausea, metallic taste, peripheral neuropathy, caecal perforation, colitis 3.Patient Satisfaction Score Timepoint: At 1 month and 3 months from date of discharge | — |
Countries
India
Contacts
Public ContactSamar Iftikhar
DR. Baba Saheb Ambedkar Hospital
Outcome results
None listed