FindTrial
Sign In

EVALUATING THE EFFICACY OF ORAL MELATONIN IN DECREASING THE HEART RATE AND BLOOD PRESSURE TO LARYNGOSCOPY AND TRACHEAL INTUBATION

TO EVALUATE THE EFFICACY OF ORAL MELATONIN IN ATTENUATING THE HAEMODYNAMIC RESPONSE TO LARYNGOSCOPY AND TRACHEAL INTUBATION

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/01/039383
Enrollment
40
Registered
2022-01-13
Start date
Unknown
Completion date
Unknown
Last updated
2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

None listed

Sponsors

DR VINUTHA PATIL C N
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age between 18 â?? 45 years of either sex. 2. Patients belonging to American Society of Anaesthesiologist (ASA) grade 1 and 2 patients.

Exclusion criteria

Exclusion criteria: 1) Refusal to consent for study. 2) Patients Receiving treatment with the study drug (melatonin). 3) Patients with 1. Uncontrolled hypertension and diabetes. 2. Mental illness, Severe Cardiac illness and Renal or hepatic disease. 3. Pregnancy and lactation. 4. Anticipated difficult intubation [Modified Mallampati class 3 and 4] 5. Patients on Hypnotics, Sedatives, anxiolytics, anti-epileptics. 6. History of allergy to melatonin.

Design outcomes

Primary

MeasureTime frame
To evaluate the effect of oral melatonin in attenuating the Blood Pressure (BP) and heart rate (HR) responses following laryngoscopy and endotracheal intubationTimepoint: AT INTUBATION AND EVERY MINUTE FOR THE FIRST FIVE MINUTES—

Secondary

MeasureTime frame
â?¢To assess the level of sedation before induction of anaesthesiaTimepoint: PERIOPERATIVE PERIOD—

Countries

India

Contacts

Public ContactDR VINUTHA PATIL C N

DR. B R AMBEDKAR MEDICAL COLLEGE AND HOSPITAL

drsalim_iqbal@yahoo.co.in9964651079

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026