None listed
Conditions
Interventions
Intervention1: Mifepristone
Misoprostol: Mifepristone 200mg given orally followed by misoprostol 800mcg pervaginally after 6-8hrs of mifepristone
Control Intervention1: Mifepristone
Misoprostol: Mifep
Sponsors
SDM College of medical sciences and hospital
Eligibility
Inclusion criteria
Inclusion criteria: Only women with a visible intrauterine gestational sac were enrolled. Mean sac diameter (length width depth/3) was used to determine estimated gestational age (EGA) only when an embryonic pole was absent. Last menstrual period was used to determine EGA if the last menstrual period was within 3 days of the ultrasound EGA; however, the ultrasound estimate was used if it differed by 4 days or more from the EGA by last menstrual period.
Exclusion criteria
Exclusion criteria: Potential subjects were EXCLUDED if they had any contraindication to mifepristone, including chronic systemic corticosteroid administration or adrenal disease; had any contraindications to misoprostol, including glaucoma, mitral stenosis, sickle cell anemia, poorly controlled seizure disorder, or known allergy to prostaglandin; had cardiovascular disease, including angina, valvular disease, arrhythmia, or cardiac failure; had a known coagulopathy or were receiving treatment with anticoagulants; had a pregnancy with an intrauterine device in utero; had active cervicitis on examination; if their ultrasound examination results demonstrated any evidence of an early pregnancy failure, had previously participated in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| to compare- complete abortion rates in women who received mifepristone followed by vaginal misoprostol 6 to 8 hours later (experimental group) and 24 hours later (standard care group) Timepoint: Complete abortion | — |
Secondary
| Measure | Time frame |
|---|---|
| side effects, bleeding, and acceptabilityTimepoint: Side effects, bleeding and acceptability | — |
Countries
India
Contacts
Public Contactmahalakshmi gaddi
SDM College of medical sciences and hospital
Outcome results
None listed