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Does intravenous anaesthesia with propofol decrease the incidence of nausea and vomiting following posterior fossa surgeries of the brain- a comparison with inhalational based anaesthesia

Incidence of post-operative nausea and vomiting in posterior cranial fossa surgery- A comparison of total intravenous vs inhalational anaesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/01/039338
Enrollment
38
Registered
2022-01-11
Start date
Unknown
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Total Intravenous Anaesthesia: Propofol intravenous infusion (Target controlled Infusion for a plasma concentration of 3-5 microgram per ml) Control Intervention1: Inhalational Anaesthe

Sponsors

Amrita Institute of Medical Sciences and Research Centre
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients of age >18 and ASA 1 and 2 physical status Elective posterior cranial fossa (infratentorial) surgeries

Exclusion criteria

Exclusion criteria: ASA 3 and 4 physical status Emergency craniotomy Preoperative GCS Patients regularly on anti-emetics Patients extubated >2h after surgery completion

Design outcomes

Primary

MeasureTime frame
Post-operative Nausea and vomiting as assessed by PONV Impact scaleTimepoint: 24 hours post-operatively—

Secondary

MeasureTime frame
to compare the recovery characteristics of patients receiving inhalational anaesthesia versus Total Intravenous AnaesthesiaTimepoint: GCS will be assesses at 0.5 hours, 1 hour and 6 hours post-operatively—

Countries

India

Contacts

Public ContactDr Avanthi Subramanian

Amrita Institute of Medical Sciences and Research centre

mathew.doc@gmail.com04842851234

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026