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To study Shatapushpa Churna effects in animal study & in patients of Polycystic Ovarian Syndrome.

In vitro and controlled clinical study of shatapushpa churna in polycystic ovarian syndrome

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/01/039331
Enrollment
100
Registered
2022-01-11
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E282- Polycystic ovarian syndrome

Interventions

Intervention1: Shatapushpa Churna 10 gms, Orally: Shatapushpa dry seeds are purchased from the available source in market.Its fine powder is prepared as per the standard norms mentioned in Ayurvedic T

Sponsors

DrRutuja SGaikwad
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: -All married & unmarried cases -USG with polycystic ovaries showing multiple small peripheral follicles( >12 follicles)in each ovary measuring 2-9mm in diameter and/or increased ovarian volume >10mm. -All cases of PCOS having amenorrhoea/oligomenorrhoea. -PCOS patients having signs of hyperandrogenism

Exclusion criteria

Exclusion criteria: -Amenorrhoea of menopause -Patients of PCOS with DM/HTN/Hypothyroidism/Hyperthyroidism/TB/HIV/HbSAg/VDRL -Cases of prgnancy,cervical tumor/polyp, uterine fibroid -known cases of systemic illness like asthma,cardiovascular and renal diseases,malignancy, Salpingo oophoritis, Cervical erosion, anatomical defective genitalia

Design outcomes

Primary

MeasureTime frame
-To observe the histopathological changes & steroidogenic enzyme activity in ovary in the Laterozole induced PCOS rat animal after administration of Shatapushpa churna -To evaluate the ovulatory effects of Shatapushpa churna in Latrazole induced PCOS in rat animal -To study the clinical action of Shatapushpa Churna in PCOS by assessing ovulatory effects ,reduction in ovarion volume and status of menstruation.Timepoint: 9 MONTHS

Secondary

MeasureTime frame
-To evaluate the effects of Shatapushpa churna in PCOS by assessing the changes in biochemical markers like FSH LH E2 TESTOSTERON DHEAS GTT SERUM LIPID PROFILE SERUM INSULIN LEVEL -To assess the effect of Shatapushpa churna in Achanthosis Nigrans Hirsutism AcneTimepoint: 9 MONTHS

Countries

India

Contacts

Public ContactDr Rutuja Sandeep Gaikwad

R A Podar Ayurved Medical College

drdewaikar@gmail.com9869079197

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026