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iv Ketamine vs palonosetron in the prevention of post-spinal anaesthesia shivering following lscs

A Comparative study of intravenous low dose Ketamine and palonosetron in the prevention of post-spinal anaesthesia shivering following cesarean section â?? A randomized control trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/01/039225
Enrollment
102
Registered
2022-01-06
Start date
Unknown
Completion date
Unknown
Last updated
2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O00-O9A- Pregnancy, childbirth and the puerperium

Interventions

Intervention1: administering the study drugs intravenously: The study drugs and normal saline will be prepared in 5ml coded syringes and presented to anaesthetists who were blinded to study group allo

Sponsors

chettinad hospital and research institute
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: american society of anaesthesiologist grade 2 patients coming for elective and emergency caesarean section

Exclusion criteria

Exclusion criteria: 1.patient not willing to be in study group 2.patients with allergic reaction to study drug 3.patients undergoing General Anaesthesia 4.patients with hypovolemia 5.Patients with stenotic valve diseases 6. patients with infection at the site of administering spinal anaesthesia 7.Patients with coagulopathy

Design outcomes

Primary

MeasureTime frame
Prevention of shivering post spinal anaesthesia after IV Ketamine 0.2 mg/kg and IV Palanosetron 0.075 mgTimepoint: Baseline , Every 5 Minutes until the end of surgery Every 10 minutes in the PostOperative period for 1 hour

Secondary

MeasureTime frame
to assess any other adverse effects and prevention of postoperative nausea and vomitingTimepoint: Baseline , Every 5 Minutes until the end of surgery Every 10 minutes in the PostOperative period for 1 hour

Countries

India

Contacts

Public ContactMerlin Shalini Ruth

chettinad hospital and research institute

merlin5shalini@gmail.com9790983957

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026