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Evaluation of echocardiographic indices to predict how infants less than 28 days respond to intravenous fluid bolus in peri-operative period

ASSESSMENT OF FLOW-BASED DYNAMIC INDICES TO PREDICT FLUID RESPONSIVENESS IN NEONATES

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/01/039217
Enrollment
66
Registered
2022-01-06
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

None listed

Sponsors

Department of Anaesthesia and Intensive Care
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Late preterm ( >34 weeks of gestational age) and term neonates upto 28 days of age scheduled for elective or emergency non-thoracic and non-cardiac surgeries

Exclusion criteria

Exclusion criteria: Congenital heart disease Cardiac arrhythmias Neonates on inotropic and/ or vasoactive support Pneumonia/ Atelectasis Denial to participate in the study

Design outcomes

Primary

MeasureTime frame
Respiratory variations in peak velocity of aortic blood flowTimepoint: 1. Baseline immediately after induction of anaesthesia. As a standard of care, an i.v. bolus of 10 ml/kg Ringers Lactate will be administered over 10 minutes after taking baseline measurement. 2. Second measurement will be done 2 minutes after end of i.v. fluid bolus

Secondary

MeasureTime frame
Respiratory variations in velocity time integral of aortic blood flow and plethysmographic variablility indexTimepoint: 1. Baseline immediately after induction of anaesthesia. As a standard of care, an i.v. bolus of 10 ml/kg Ringers Lactate will be administered over 10 minutes after baseline measurements. 2. Second measurements will be done 2 minutes after end of i.v. fluid bolus.

Countries

India

Contacts

Public ContactPreethy J Mathew

PGIMER

tjpreethy@gmail.com9417800203

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026