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change in the level of blood immunity before and after epidural anesthesia in patients undergoing breast cancer surgery

Immunomodulatory effects of epidural anesthesia in patients with breast cancer undergoing breast cancer surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/01/039127
Enrollment
20
Registered
2022-01-04
Start date
Unknown
Completion date
Unknown
Last updated
2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C509- Malignant neoplasm of breast of unspecified site

Interventions

None listed

Sponsors

Amrita Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA 2 patients who are scheduled for breast surgeries for breast cancer under epidural anaesthesia

Exclusion criteria

Exclusion criteria: 1. Any contraindication for regional anaesthesia 2. Patients who have difficulty in lying down supine 3. Uncooperative/ Psychiatric patients 4. Endocrinological diseases 5. Immunological diseases 6. Chronic liver disease 7. Chronic pain 8. Signs of infection 9. Allergic to any of the study medication

Design outcomes

Primary

MeasureTime frame
To assess the change in proinflammatory mediator IL6 before and after epidural anaesthesiaTimepoint: Before and 2 hours after anaesthesia—

Secondary

MeasureTime frame
To assess the change in serum levels of TNF α, IL1β, IL10, IFN γ, IL 2, leucocytes, lymphocytes, neutrophils, monocytes, eosinophils and basophils caused by induction of epidural anaesthesia.Timepoint: Before and 2 hours after anaesthesia—

Countries

India

Contacts

Public ContactSharavanan

Amrita Institute of medical Sciences

nituveesundeep@gmail.com09495962020

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026