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Trial of tDCS as Early Augmentation in Adults with Depression

Randomised Controlled Single Blind Trial of Transcranial Direct Current Stimulation (tDCS) as Early Augmentation in Major Depressive Disorder

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/01/039123
Enrollment
40
Registered
2022-01-04
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F332- Major depressive disorder, recurrent severe without psychotic features Health Condition 2: F331- Major depressive disorder, recurrent, moderate Health Condition 3: F321- Major depressive disorder, singleepisode, moderate Health Condition 4: F322- Major depressive disorder, singleepisode, severe without psychotic features

Interventions

Intervention1: Active Transcranial Direct Current Stimulation (tDCS): A total of 10 sessions (on a daily basis) of tDCS will be delivered over a period of two weeks following a uniform treatment proto

Sponsors

King Georges Medical University Lucknow
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age 18-60 years 2. Patients diagnosed with Major Depressive Disorder according to DSM-5 3. Willing to give Informed consent to participate in the study. 4. Drug Naive (at least drug free for the past 1 month)

Exclusion criteria

Exclusion criteria: 1. Patients with Treatment Resistant Depression. 2. Patients having Psychotic Depression. Suicidal Patients 3. HAM-D (Hamilton Depression Rating Scale) less than 13 4. Medical co-morbidities that need immediate attention. 5. Any contraindications to tDCS. 6. Patients with any other co-morbid psychiatric disorder except Tobacco use disorders.

Design outcomes

Primary

MeasureTime frame
To study efficacy of transcranial direct current stimulation in Major Depressive DisorderTimepoint: Assessment at 0, 2 and 4 weeks

Secondary

MeasureTime frame
To study safety of transcranial direct current stimulation in Major Depressive DisorderTimepoint: Assessment at each session

Countries

India

Contacts

Public ContactBabli Kumari

King Georges Medical University, Lucknow

drsujita@gmail.com9956273747

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 9, 2026