DEVELOPMENT OF AN INNOVATIVE HERBAL PATCH AND EVALUATION OF ITS COMPARATIVE CLINICAL EFFICACY IN KNEE OSTEOARTHRITIS

DEVELOPMENT OF AN INNOVATIVE UPANAHA PATCH AND EVALUATION OF ITS COMPARATIVE CLINICAL EFFICACY IN KNEE OSTEOARTHRITIS

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/01/039114

Enrollment

100

Registered

2022-01-04

Start date

Unknown

Completion date

Unknown

Last updated

2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M170- Bilateral primary osteoarthritis of knee

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients suffering from classical signs and symptoms of Sandhigatavata. 2. Patients with unilateral or bilateral knee OA. 3. Chronicity less than or equal to grade 3 Moderate OA. ie.Frequent pain during movement, joint stiffness also present especially during long sitting and in morning period. The cartilage between the bones shows obvious damage, and the space between the bones is getting smaller. 4.Patient fit for Kolakulathadi Upanaha. 5.Average knee pain in the last week during weight bearing activities of atleast 4 on a 0 to 10 points VAS for pain.0 means â??no pain 10â??meansâ??worst possible pain 6. Patient without any anatomical deformity in Knee Joint.

Exclusion criteria

Exclusion criteria: Patients with skin diseases. Patients suffering from Gout, Rheumatoid arthritis, Systemic Lupus Erythematous , Bone TB, psoriatic arthritis and other serious systemic disorders. Patients contraindicated for Swedana. Open wounds on the knee joint. Allergic skin condition. Knee replacement surgical cases.

Design outcomes

Primary

Measure	Time frame
Development of an innovative upanaha patch for easy adaptability and its standardization.Timepoint: 0,7,21	—

Secondary

Measure	Time frame
1. Reduction in pain and swelling as per VAS scale and WOMAC index in knee osteoarthritis after Kolakulathadi Upanaha and Kolakulathadi Upanaha Patch. 2. Changes in CRP, IL-6. 3. To evaluate the improvement in the quality of life after Kolakulathadi Upanaha. 4. Comparative compliance of Kolakulathadi Upanaha and Upanaha Patch. Timepoint: 0th day, 7th day, 21st day	—

Countries

India

Contacts

Public ContactYOSHITHA C N

All India Institute of Ayurveda

drprasanthd@gmail.com9895174060

Outcome results