Rising the temperature and reducing the flow rate of fluid meant for exchange of waste products from blood in hemo ( blood ) dialysis and its impact on removal of waste products in end stage kidney disease patients - a strategy for conservation of water

Increasing dialysate temperature and reducing dialysate flow rate - Impact on solute clearance and a strategy for water conservation

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/01/039108

Enrollment

Registered

2022-01-04

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N186- End stage renal disease

Interventions

Intervention1: Increasing the Dialysate temperature to 38.5 degree centigrade and reducing the dialysate flow to 300 ml per minute: Increasing the Dialysate temperature from 37 degree to 38.5 degree

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients with well functioning AVFistula. 2.Dialysis vintage more than 3 months. 3.No previous episodes of recurrent intradialytic hypotension. 4.left ventricle Ejection fraction > 40%.

Exclusion criteria

Exclusion criteria: 1.Patients with tunneled or non tunneled catheters as the dialysis access. 2.Patients with recurrent intradialytic hypotension. 3.Patients with autonomic neuropathy. 4.Patients with left ventricle Ejection fractionÃ?â??40%.

Design outcomes

Primary

Measure	Time frame
1.Urea reduction ratio in every session of hemodialysis. 2. calculation of online Kt/V and time to reach the target of 1.2 in every session of dialysis.Timepoint: one month each for intervention and comparator arm that includes 8 to 12 session of hemodialysis	—

Secondary

Measure	Time frame
1. number of episodes of intradialytic hypotensionTimepoint: one month each for intervention and comparator arm that includes 8 to 12 session of hemodialysis	—

Countries

India

Contacts

Public ContactDolphin solomon J

madras medical college

draatral@gmail.com09444126080

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026