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Study of effectiveness of dexmedetomidine, when added to bupivacaine in spinal anaesthesia for lower limb surgery

Effect of intrathecal Dexmedetomidine as an adjuvant to hyperbaric bupivacaine in orthopaedic lower limb surgery: An Intervention Study

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/01/039100
Enrollment
50
Registered
2022-01-03
Start date
Unknown
Completion date
Unknown
Last updated
2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: dexmedetomidine: 5 mcg added to 2.5ml bupivacaine 0.5% heavy,single dose Control Intervention1: control: 2.5ml bupivacaine 0.5% heavy with 0.5ml normal saline,single dose

Sponsors

Department of Anaesthesiology
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Age 18 to 65 years 2.Both genders 3.ASA grade I and II

Exclusion criteria

Exclusion criteria: 1.History of spine surgery, hepatic failure, neuromuscular disorders 2.chronic history of headache, backache and infection in back 3.Any absolute or relative contraindication to study drug 4.Uncooperative patients 5.Coagulopathy 6.Patient with history of cardiac or respiratory diseases

Design outcomes

Primary

MeasureTime frame
motor block regression in bromage score,sensory block regression by pin prick sensationTimepoint: 6 to 8 hours after intrathecal injection

Secondary

MeasureTime frame
Onset of Sensory and motor block, Hemodynamic alterations, Numeric Rating Scale 6 hours after surgery.Timepoint: 0 min,5 min,10 min,15 min, 20 min,25 min,30 min,45 min, 60 min,75 min,90 min,105 min, 120 min,240 min,360 min.

Countries

India

Contacts

Public ContactDr Fateh Singh Bhati

Dr S.N.Medical College,Jodhpur

fatehbhati68@gmail.com9414127176

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026