To assess the outcome of two different methods of pulpotomy in carious exposed and painful permanent teeth.

Outcome of coronal and deep pulpotomy in mature permanent teeth with extremely deep carious lesion and symptomatic irreversible pulpitis- A preliminary randomized clinical trial (Pilot study)

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/12/039044

Enrollment

Registered

2021-12-30

Start date

Unknown

Completion date

Unknown

Last updated

2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K02- Dental caries

Interventions

Intervention1: Deep Pulpotomy: Deep pulpotomy is a procedure which involves removal of vital pulp tissue 2mm apical to the level of root canal orifice and application of a biomaterial directly on to t

Eligibility

Inclusion criteria

Inclusion criteria: 1)Healthy patients with mature mandibular 1st & 2nd molar with established clinical diagnosis of symptomatic irreversible pulpitis without periapical rarefaction. 2)Radiographically extremely deep carious lesion penetrating the entire thickness of the dentin, without a radio-dense zone. 3)Positive response to cold and electric pulp test. 4)Teeth with restorable carious lesion.

Exclusion criteria

Exclusion criteria: 1)Deep carious lesions extending >=3/4 of the dentine thickness, with a visible radiopaque zone separating the carious lesion from the pulp, of mature permanent teeth with symptomatic irreversible pulpitis 2)Extremely deep carious lesion with periapical rarefaction. 3)Teeth with cracks, cusp fractures, subgingival caries and poor periodontal health 4)Patients with systemic conditions which could compromise the healing. 5)Patients not willing to participate in the study. Intraoperative exclusion criteria: 1)Bleeding that cannot be controlled within 10 minutes with 2.5% NaOCl wet cotton pellet 2)Clinical diagnosis changes to pulpal necrosis.

Design outcomes

Primary

Measure	Time frame
Primary Outcome: 1) Clinical Outcome: Absence of clinical signs/symptoms including pain on percussion/palpation, apical periodontitis, sinus tract and deep periodontal pockets. 2) Radiographic Outcome: Normal PDL space (PI score â?¤2), absence of internal/external root resorption & furcal radiolucency. Timepoint: 3 months 6 months 12 months	—

Secondary

Measure	Time frame
Secondary Outcome: 1) Positive response to electric pulp sensibility test. Timepoint: 3 months 6 months 12 months	—

Countries

India

Contacts

Public ContactDr Vijay Kumar

All India Institute of Medical Sciences, New Delhi

aaqibshah100@gmail.com7889385745

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026