Health Condition 1: - Health Condition 2: G438- Other migraine
Conditions
Interventions
Intervention1: compare the efficacy of Propranalol and Flunarizine for prophylaxis in pediatric migraine: The ones fulfilling the inclusion criteria after the prospective period will be enrolled into
Sponsors
Pandit BDSharma UHSRPGIMS ROHTAK
Eligibility
Inclusion criteria
Inclusion criteria: Children aged 7 to 14 years with migraine with a score of 11 to 139 on Pediatric migraine Disability Assessment Score(PedMIDAS) and a headache frequency of 4 or more days per month over a baseline period of 28 days.
Exclusion criteria
Exclusion criteria: Children with either of the following conditions will be excluded chronic liver disease, chronic kidney disease, hypertension (BP >95TH percentile for age, sex, and height; or 130/80 mm hg for age >13yr) diabetes, (fasting plasma glucose 126 mg/dl or 2hr plasma glucose during OGTT 200 mg/dl) epilepsy, Obesity (BMI >95th percentile for age and sex) Asthma
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome will be proportion of children with a relative reduction of 50% or more in the number of headache days in comparison of 28 day baseline period with the last 28 days of 12 week trial period.Timepoint: 16 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare headache disability,absolute reduction in number of headache days and the safety of Propranalol and Flunarizine in prophylaxis of pediatric migraineTimepoint: 16 weeks | — |
Countries
India
Contacts
Public ContactDr Preet
Pt. B.D. Sharma PGIMS Rohtak
Outcome results
None listed