A study to compare the efficacy of Silver and Zinc oxide Nanoparticles in strengthening the antifungal properties of acrylic resin prostheses for type 2 diabetic patients.

The efficiency of silver and zinc oxide nanoparticles reinforcement on the antifungal and mechanical properties of polymethyl methacrylate resin prosthesis in type 2 diabetic patients.

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/12/038998

Enrollment

Registered

2021-12-28

Start date

Unknown

Completion date

Unknown

Last updated

2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K121- Other forms of stomatitis

Interventions

Intervention1: Complete Denture Prosthesis: Acrylic resin Complete Denture Prosthesis for Type II Diabetic Patients Control Intervention1: 0.5% Silver nanoparticles: The 0.5% Silver nanoparticles are

Eligibility

Inclusion criteria

Inclusion criteria: Type 2 Diabetic completely edentulous patients with HbA1c level equal or more than 7

Exclusion criteria

Exclusion criteria: Completely edentulous patients with any other systemic disease other than diabetic Mellitus

Design outcomes

Primary

Measure	Time frame
Reduction of microbial count in the surface of acrylic resin prosthesisTimepoint: one week, one month and six month	—

Secondary

Measure	Time frame
comparing with HbA1c levels with reduction amount of fungal count and also with age and sex parametersTimepoint: one week, one month and six month	—

Countries

India

Contacts

Public ContactN Parthasarathy

Sri Ramachandra Institute of Higher Education and Research

parthasarathy.n@sriramachandra.edu.in9840674772

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026