Comparing the onset and duration of motor blockade and sensory blockade between nalbuphine and buprenorphine when used with ropivacaine in epidural anaesthesia for lower abdomen and lower limb surgeries

Comparison of nalbuphine versus buprenorphine as an adjuvant to epidural ropivacaine in lower abdomen and lower limb surgeries

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/12/038997

Enrollment

Registered

2021-12-28

Start date

Unknown

Completion date

Unknown

Last updated

2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Nalbuphine: nalbuphine 10mg with 0.75% ropivacaine via edidural cathter into the epidural space . duration of intervention is the time taken for the drug to produce anaesthesia Control

Eligibility

Inclusion criteria

Inclusion criteria: 1)ASA 1 & 2 2)Age 18 to 60 years of both sex 3) Patients undergoing elective lower abdomen and lower limb surgeries

Exclusion criteria

Exclusion criteria: 1)Patients not willing 2) allergic to specific drugs 3)pregnant women 4) contraindications for epidural anesthesia 5)intraoperative surgical complications like massive blood loss & haemodynamic instability 6)Patients with sensory & motor deficit

Design outcomes

Primary

Measure	Time frame
Onset of sensory block Onset of motor block Duration of sensory and motor blockTimepoint: 0 hrs to 24 hrs	—

Secondary

Measure	Time frame
Nausea Vomiting Pruritis ShiveringTimepoint: 0 hrs to 24 hrs	—

Countries

India

Contacts

Public ContactASWIN

SRI VENKATESWARAA MEDICAL COLLEGE HOSPITAL AND RESEARCH CENTER

rkpuduvai@gmail.com8825778958

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026