Health Condition 1: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx
Conditions
Interventions
Intervention1: PETCECT: POSITRON EMISSION COMPUTERIZED TOMOGRAHY AS AN INITIAL ASSESSMENT FOR ORAL CANCER.
PATIENTS RANDOMIZED INTO THIS ARM WILL UNDERGO PET CECT AS THE RADIOLOGICAL ASSESSMENT FOR
Sponsors
ALL INDIA INSTITUTE OF MEDICAL SCIENCES RAIPUR
Eligibility
Inclusion criteria
Inclusion criteria: 1.1.1 Histologically proven, treatment naïve oral cavity cancers. 1.1.2 Oral cancers amenable for a surgery as a primary treatment modality. 1.1.3 Aged between 18 to 75 years. 1.1.4 ECOG status 0 to 2
Exclusion criteria
Exclusion criteria: 1.2.1 Neoadjuvant chemotherapy prior to surgery 1.2.2 Previous oncological treatment 1.2.3 Recurrent or second primary tumours 1.2.4 ASA more than III 1.2.5 PETCECT as an initial investigation of choice for advanced stage disease as deemed necessary by the tumour board.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine sensitivity, specificity, negative predictive value, and positive predictive value of PET CECT, CECT and MRI for determining the primary tumour, and nodal metastasis (Part 1 and Part 2)Timepoint: AT BASELINE | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To determine the cut-off maximum Standard Uptake Value (SUVmax) for neck nodal metastasis. (Part 1) 2. To determine the cut-off maximum Standard Uptake Value (SUVmax) for primary tumour margin. (Part 2) 3. To create a real world high quality evidence, by comparing the exiting literature as a meta-analysis with our results (Part 2 of study)Timepoint: AT BASELINE | — |
Countries
India
Contacts
Public ContactKARTHIK NAGARAJA RAO
ALL INDIA INSTITUTE OF MEDICAL SCIENCES, RAIPUR
Outcome results
None listed