Health Condition 1: L918- Other hypertrophic disorders of the skin
Conditions
Interventions
Intervention1: Nil: Nil
Control Intervention1: Nil: Nil
Sponsors
IADVL Indian Association of Dermatology Venereology and Leprosy
Eligibility
Inclusion criteria
Inclusion criteria: Individuals diagnosed with keloid (scar spread beyond original borders and no spontaneous regression within 1 year) Having taken no treatment for keloids before (Treatment naïve) Not on any immunomodulator drugs for other conditions Male and female Above 18 years age .
Exclusion criteria
Exclusion criteria: ï?? Mixed or unclear diagnosis ï?? Pregnant/lactating females ï?? Patients who refuse to participate in the study ï?? Patients having other diseases like diabetes, or with communicable diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The proposed study is an exploratory study to understand the relation between melanocytes and fibroblasts in keloids. It is not a clinical trial, and hence no success/failure is involved. Understanding the effect of modulation of melanin content in melanocytes on the fibroblast biologyTimepoint: 1 year | — |
Secondary
| Measure | Time frame |
|---|---|
| Understanding the effect of melanocyte-conditioned media (melanocyte secretome) on fibroblast biology (trans-well co-culture set up).Timepoint: 1 year | — |
Countries
India
Contacts
Public ContactAayush Gupta
Dr. D.Y. Patil Medical College, Hospital and Research centre
Outcome results
None listed