A study to see if adding magnesium sulphate to local anaesthetic in abdominal block decreases pain after gall bladder surgery

Magnesium sulphate as adjuvant to ropivacaine in bilateral transversus abdominis plane block for laproscopic cholecystectomy.

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/12/038916

Enrollment

Registered

2021-12-24

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K802- Calculus of gallbladder without cholecystitis Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Ultrasound guided subcostal TAP block will performed on both sides using 20 ml volume (19.5 ml of 0.2 % ropivacaine plus 0.5 ml Magnesium sulphate 50%): Drug: Ropivacaine plus Magnesium

Eligibility

Inclusion criteria

Inclusion criteria: Adult patients aged 18-65 years undergoing laparoscopic cholecystectomy

Exclusion criteria

Exclusion criteria: 1.Patient refusal 2.Patients with a history of cardiac, or respiratory diseases ( >ASA III). 3.Patients with allergy to amide local anesthetics or medication included in the study. 4.Infection at the needle insertion site. 5.Pregnancy 6.BMI >35 7.Drug abusers

Design outcomes

Primary

Measure	Time frame
The post-operative pain during first 24 hours after surgery using Visual analogue scale.Timepoint: 24 hours	—

Secondary

Measure	Time frame
1. Time to first dose of post-operative analgesia and total diclofenac consumption in 24 hours 2. Post-operative nausea and vomiting 3. Sedation 4. Patient satisfaction Timepoint: 24 hours	—

Countries

India

Contacts

Public ContactWasim Mohammad Bhat

SKIMS Medical College Bemina

wmb914@gmail.com7006142879

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026