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To compare bupivacaine and ropivacaine in for post-operative pain relief after Elective Abdominal Hysterectomy.

Comparison of Ropivacaine (0.75%) and Bupivacaine (0.5%) in bilateral transversus abdominis plane block for post-operative analgesia in Elective Abdominal Hysterectomy under Sub-arachnoid block

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/12/038898
Enrollment
64
Registered
2021-12-24
Start date
Unknown
Completion date
Unknown
Last updated
2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N92- Excessive, frequent and irregularmenstruation Health Condition 2: D25- Leiomyoma of uterus Health Condition 3: O- Medical and Surgical Health Condition 4: N93- Other abnormal uterine and vaginalbleeding

Interventions

Intervention1: INJ BUPIVACAINE: INJ BUPIVACAINE(0.50%) DOSE 15ml on each side (total 30ml) frequency : single dose route : intramuscular Control Intervention1: INJ ROPIVACAINE: INJ ROPIVACAINE(0.75%)

Sponsors

Government medical collegeBhavnagar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing elective abdominal hysterectomy under subarachnoid block. Age: 35-65 years ASA(American society of anaesthesia) physical status I and II.

Exclusion criteria

Exclusion criteria: Contraindications to subarachnoid block like, - Local infection or sepsis at the site of Lumbar puncture - Bleeding disorders, thrombocytopenia - Space occupying lesions of the brain - Anatomical disorders of the spine - Hypovolaemia e.g. following massive haemorrhage Allergy to local anaesthetic drugs . Pregnancy and lactation Patient on any form of analgesics therapy.

Design outcomes

Primary

MeasureTime frame
TO COMPARE EFFECTIVENESS OF BUPIVACAINE(0.5%) AND ROPIVACAINE(0.75%) FOR POST OPERATIVE ANALGESIA IN BILATERAL TRANSVERSUS ABDOMINIS PLANE BLOCKTimepoint: 24 hours—

Secondary

MeasureTime frame
TO COMPARE BETWEEN 2 GROUPS 1)Frequency and duration of rescue analgesia required in first 24 hours 2)Time for first rescue analgesic 3)Effect on hemodynamic variables like heart Rate (HR) , Mean Arterial Pressure (MAP), Oxygen saturation(SpO2 ) 4)Frequency of Side effects like bradycardia,hypotension, nausea , vomiting Timepoint: 24 hours—

Countries

India

Contacts

Public ContactDr kaushikkumar vaniya

GOVERNMENT MEDICAL COLLEGE,BHAVNAGAR

drshilpadoshi@yahoo.in9428810763

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026