FindTrial
Sign In

Effect of topical Ropivacaine on extubation response in patients undergoing neurosurgery

Effect of Topical Ropivacaine on Extubation Response in patients undergoing supratentorial tumours:A Prospective Randomised Double Blinded Placebo Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/12/038820
Enrollment
72
Registered
2021-12-21
Start date
Unknown
Completion date
Unknown
Last updated
2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: D330- Benign neoplasm of brain, supratentorial Health Condition 2: C719- Malignant neoplasm of brain, unspecified Health Condition 3: O- Medical and Surgical Health Condition 4: O- Medical and Surgical

Interventions

Intervention1: ROPIVACAINE: After keeping the bone flap in its original position when the scalp muscle suturing will commence we will instilled 6 ml of 0.5% ropivacaine topically in study group throu

Sponsors

Department of Neuroanesthesiology and Critical care AIIMS New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients between 18 â?? 65 years of age. 2. ASA grade I & II patients. 3. Patients posted for elective surgergy for supratentorial tumours

Exclusion criteria

Exclusion criteria: 1. Refusal of consent 2. Patients with history of smoking or chronic cough 3. Patients with history of upper respiratory tract infection (URI) in last 8 weeks 4. Patients with bleeding disorders 5. Previous laryngeal or tracheal surgery or pathology 6. Patients with history of gastric reflux 7. Patients with preoperative GCS 8. Patients with pulmonary disease, renal, cardiac or hepatic disorders, uncontrolled diabetes or blood pressure 9. Delayed extubation (more than 1 hr) 10. Patients with BMI > 35kg/mt2 11. Allergy to study drugs

Design outcomes

Primary

MeasureTime frame
To compare the incidence of cough between preservative free 0.5% topical ropivacaine and placebo during extubation in patients undergoing supratentorial tumour surgeriesTimepoint: Till 5 minutes after extubation—

Secondary

MeasureTime frame
1. To determine the effect of topical ropivacaine on heart rate and blood pressure(SBP,DBP,MAP) changes during emergence in patients undergoing supratentorial tumour surgeries. 2. To determine the effect of topical ropivacaine on the emergence time, extubation time and recovery time in these patients 3. To determine the effect of topical ropivacaine on the neurological recovery(modified Aldrete score) and sore throat in the early postoperative period in these patients Timepoint: Till one hour after extubation—

Countries

India

Contacts

Public ContactDr NIRAJ KUMAR

AIIMS, New Delhi

drnirajaiims@gmail.com9013770806

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026