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Antibiotic used in Inguinal Hernia repair

Comparative study between single dose and multiple dose Cefotaxime to evaluate Surgical Site Infection in patients undergoing Elective Mesh Hernioplasty

Status
Active, not recruiting
Phases
Phase 1Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/12/038794
Enrollment
66
Registered
2021-12-21
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K402- Bilateral inguinal hernia, withoutobstruction or gangrene

Interventions

Intervention1: Cefotaxime: Cefotaxime 1gm intravenous at the time of induction for group A patients, Cefotaxime 1gm intravenous at the time of induction followed by Cefotaxime 1gm intravenous,BD for

Sponsors

Dr Samit Doshi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) All patients undergoing elective open inguinal mesh hernioplasty. 2) Patients with Unilateral inguinal hernia and Bilateral inguinal hernia. 3) Patients giving consent for taking part in the study. 4) Patients above 18 years of age. 5) All clean hernia surgeries.

Exclusion criteria

Exclusion criteria: 1) Patients below 18 years of age. 2) All the other hernias except inguinal hernias. 3) Patients on steroid treatment or patients with immunosuppressed states and malignancy. 4) Patients having local site infections like Tinea or Scabies. 5) All patients with complicated hernia such as Irreducible hernia, Obstructed hernia and Strangulated hernia. 6) All patients allergic to Cephalosporins. 7) All Laparoscopic hernia repairs. 8) All Recurrent inguinal hernias. 9) All clean-contaminated, contaminated and dirty hernia surgeries.

Design outcomes

Primary

MeasureTime frame
From this study it is expected that 1) multiple dose Cefotaxime does not cause a significant decrease in the rate of surgical site infection compared to single dose Cefotaxime 2) Lower treatment costs for the patient and is cost effective 3) Reduce the spread of antibiotic resistance 4) Avoidance of side effects due to overuse of antibiotics 5) Reduce hospital stayTimepoint: Assessment of patients to evaluate surgical site infection on day 3 day 5 day 7 day 15 and day 30

Secondary

MeasureTime frame
noneTimepoint: none

Countries

India

Contacts

Public ContactDr Samit Doshi

MGM Institute of Health Sciences Navi Mumbai

dr.sameerkadam@gmail.com9594773336

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026