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Effectiveness of ketamine nebulization in reducing sore throat after an operation under general anasthesia

â??Safety and efficacy of ketamine nebulization to reduce postoperative sore throat in patients undergoing general anaesthesia- Prospective, randomised single blind placebo controlled studyâ??

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/12/038764
Enrollment
60
Registered
2021-12-20
Start date
Unknown
Completion date
Unknown
Last updated
2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Ketamine nebulisation: Ketamine nebulisation preoperatively for one time Duration of therapy for 10 min Control Intervention1: Normal saline nebulisation: Normal saline nebulisation pre

Sponsors

GOVT MEDICAL COLLEGE BHAVNAGAR
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing general anaesthesia with endotracheal intubation.

Exclusion criteria

Exclusion criteria: 1)Patients with a history of pre operative sore throat ,oral surgeries, asthma,chronic obstructive pulmonary disease, head and neck surgeries. 2) Mallampati grade >2. 3) Known allergies to study drug. 4)Recent use of non steroidal anti inflammatory medication. 5)Those who requires more than one attempt at intubation.

Design outcomes

Primary

MeasureTime frame
To assess efficacy of ketamine nebulisation in terms of incidence and severity of POSTTimepoint: 24hours—

Secondary

MeasureTime frame
to assess safety of Ketamine nebulization in terms of.. 1) side effects like postoperative nausea, vomiting and respiratory depression 2) hemodynamic stress response of a patient in terms of heart rate, blood pressure and spo2 Timepoint: Before and at 5 min, 10 min, 15 min after giving nebulisation—

Countries

India

Contacts

Public ContactDrLOPA TRIVEDI

GOVERNMENT MEDICAL COLLEGE, BHAVNAGAR

trivedi_lopa@yahoo.in9428009958

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026