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EVALUATION OF 4% MANGOSTEEN GEL AS AN ADJUNCT TO SCALING & ROOT PLANING ON CLINICAL PARAMETERS AND GCF MMP-9 LEVELS IN CHRONIC PERIODONTITIS â?? A SPLIT MOUTH STUDY

EVALUATION OF 4% MANGOSTEEN GEL AS A SUBGINGIVAL LOCAL DRUG DELIVERY IN ADJUNCT TO SCALING & ROOT PLANING ON CLINICAL PARAMETERS AND GCF MMP-9 LEVELS IN CHRONIC PERIODONTITIS PATIENTS â?? A SPLIT MOUTH STUDY

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/12/038758
Enrollment
13
Registered
2021-12-20
Start date
Unknown
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: 4% mangosteen gel: Preparation of the 4% Mangosteen gel according to Mahendra J et al.(2017) The constituents of Mangosteen gel will be prepared with the following proportions: 1. Mango

Sponsors

MANJIRI KULKARNI
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients who were systemically healthy Patients having a minimum of two sites in different quadrants with probing depths less than or equal to five mm and clinical attachment loss less than or equal to three to four mm Stage II and Grade B periodontitis requiring nonsurgical treatment Patients who did not use chemotherapeutic mouth rinses or any oral irrigation devices during the study period

Exclusion criteria

Exclusion criteria: Patients with any known or suspected drug allergy Patients with a history of chronic smoking and alcohol consumption Patients who had used both systemic and topical antibiotics and anti inflammatory agents in the last three months Patients who had received treatment for periodontitis within the previous six months Pregnant and lactating mothers Patients with a history of uncontrolled diabetes and hypertension and immunocompromised conditions Patients who were noncompliant or physically challenged and were not able to maintain oral hygiene or not able to follow up for their recall visit

Design outcomes

Primary

MeasureTime frame
TO COMPARE THE PROBING DEPTH BETWEEN EXPERIMENTAL AND CONTROL GROUPS AT THE END OF THREE MONTHSTimepoint: BASELINE TO THREE MONTHS

Secondary

MeasureTime frame
TO COMPARE THE CLINICAL ATTACHMENT LEVEL USING ACRYLIC STENT BETWEEN EXPERIMENTAL AND CONTROL SITES AT THE END OF THREE MONTHSTimepoint: BASELINE TO THREE MONTHS

Countries

India

Contacts

Public ContactMANJIRI KULKARNI

BAPUJI DENTAL COLLEGE AND HOSPITAL

gayathri_dental@rediffmail.com9886593224

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026