comparison of time for onset of action and intubating conditions using high doses of Rocuronium versus Vecuronium during intubation

Comparison of time for onset of action and intubating conditions using 4 times ED95 dose of Rocuronium versus Vecuronium during endotracheal intubation-A prospective randomized double-blind study.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/12/038729

Enrollment

Registered

2021-12-17

Start date

Unknown

Completion date

Unknown

Last updated

2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: comparision of time for onset of action and intubating conditions using 4 times ED95 dose of Rocuronium versus Vecuronium.: Using 4 times ED95 dose of vecuronium or rocuronium is dil

Eligibility

Inclusion criteria

Inclusion criteria: patients with Mallampati grade I/II. patient of American Society of Anesthesiologists physical status I,II,III Patients scheduled to undergo elective surgical procedures requiring general endotracheal anesthesia with neuromuscular paralysis.

Exclusion criteria

Exclusion criteria: 1.Obese patients (BMI > 30kg / m2) 2.Pregnant and Lactating women. 3.Patients allergic to study drugs. 4.Patients with hepatic or renal impairment , neuromuscular disorders. 5.Patients who are not willing to participate in the study.

Design outcomes

Primary

Measure	Time frame
1.To compare the time for onset of action by objectively assessing the absence of twitch response to train of four (TOF) stimulation. 2.To compare the intubating conditions during endotracheal intubation using Copenhagen consensus conference scoring system. Timepoint: 1.To compare the time for onset of action by objectively assessing the absence of twitch response to train of four (TOF-0) stimulation.	—

Measure

Time frame

1.To compare the time for onset of action by objectively assessing the absence of twitch response to train of four (TOF) stimulation. 2.To compare the intubating conditions during endotracheal intubation using Copenhagen consensus conference scoring system. Timepoint: 1.To compare the time for onset of action by objectively assessing the absence of twitch response to train of four (TOF-0) stimulation.

—

Secondary

Measure	Time frame
the conditions of putting the tube in trachea using rocuronium or vecuroniumTimepoint: after giving rocuronium or vecuronium	—

Countries

India

Contacts

Public ContactDrMMadhusudan

Sri Venkateswara Institute of Medical Sciences

drmadhu37@gmail.com9493547723

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026