Comparison of antibacterial efficacy of Diclofenac sodium and Calcium hydroxide as intracanal medicaments

Assessment of antimicrobial efficiency of Diclofenac sodium in single rooted teeth with asymptomatic apical periodontitis - A Randomized controlled, double blinded clinical trial.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2021/12/038705

Enrollment

Registered

2021-12-16

Start date

Unknown

Completion date

Unknown

Last updated

2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K041- Necrosis of pulp

Interventions

Intervention1: Diclofenac sodium: Diclofenac sodium is an NSAID available over the counter. It can be grouped under Non antibiotic with antimicrobial activity based on in vitro study results. Dose is

Eligibility

Inclusion criteria

Inclusion criteria: Asymptomatic apical periodontitis, single rooted teeth

Exclusion criteria

Exclusion criteria: Patient below18 and above 55y. Symptomatic patient

Design outcomes

Primary

Measure	Time frame
Reduction of microbial loadTimepoint: Assessed at one week	—

Secondary

Measure	Time frame
Postoperative painTimepoint: Assessed at 24h,48h, 72h, one week	—

Countries

India

Contacts

Public ContactRama Sowmya

Saveetha Dental College

nivedhitha@saveetha.com9840912367

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026