Health Condition 1: K802- Calculus of gallbladder without cholecystitis Health Condition 2: O- Medical and Surgical
Conditions
Interventions
Intervention1: Opioid Free Anaesthesia: Opioid free anaesthesia using intravenous dexamethasone 0.1 mg/kg, loading dose of dexmedetomidine 0.5 mcg/kg over 10 mins followed by an infusion of 0.5 mcg/kg
Sponsors
Department of Anaesthesiology and Intensive Care
Eligibility
Inclusion criteria
Inclusion criteria: American Society of Anaesthesiologists (ASA) Physical Status Grade I-II
Exclusion criteria
Exclusion criteria: 1.Patients with AV block or severe bradycardia 2.Patients having BMI >30 kg/m2 3.Patients with allergy to any of the study drugs 4.Patients with cardiac, renal, hepatic and psychiatric illness. 5.H/o chronic use of opioid analgesic/ chronic steroids/ NSAIDS/ or any chronic drug therapy 6.H/o alcohol abuse 7.Patients who are pregnant or are breastfeeding 8.Patients with decreased autonomic control- elderly, diabetic, chronic hypertension, severe cardiac disease, on drugs like beta blockers or calcium channel blockers 9.Patient refusal
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference in postoperative recovery using QoR-40 score 24 hours after surgery.Timepoint: 24 hours after surgery. | — |
Secondary
| Measure | Time frame |
|---|---|
| Any intraoperative bradycardia, hypotension, tachycardia, or hypertensionTimepoint: at any point of time intraoperatively;Postoperative opioid related side effectsTimepoint: within 24 hours of postoperative period;Postoperative VAS scores Timepoint: at 15 min, 30 min, 1 hr, 2 hr, 4 hr, 8 hr, 12 hr, and 24 hr postoperatively.;Requirement of postoperative analgesics in the first 24 hours after surgeryTimepoint: over first 24 hours after surgery;Sedation score in PACUTimepoint: on arrival at Post Aanaesthesia Care Unit (PACU);Time for readiness for discharge from PACU (PADSS score)Timepoint: 0 min, 15 mins, 30 mins, 45 mins, 60 mins, 1 hour 15 mins, 1 hour 30 mins, 1 hour 45 mins, 2 hours in PACU | — |
Countries
India
Contacts
Public ContactDr Anju R Bhalotra
Maulana Azad Medical College
Outcome results
None listed