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Application of blood derived growth factors in treatment of gum disease

Clinical evaluation of the combined efficacy of scaling and root planing (SRP) and injectable platelet rich fibrin (I-prf) in the non-surgical periodontal therapy of Stage III periodontitis patients - Randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/12/038681
Enrollment
15
Registered
2021-12-16
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K056- Periodontal disease, unspecified

Interventions

Intervention1: Test group: Periodontal pockets treated with scaling and root planing (SRP) + injectable platelet rich fibrin (i-PRF) application. Control Intervention1: Control group: Periodontal pock

Sponsors

Dr Anupama Tadepalli
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Subject with moderate periodontal disease with the case definition, Stage III periodontitis, according to EFP-AAP periodontal disease classification 2017. i.e., Moderate periodontal destruction is defined as sites having � 5mm probing pocket depth with attachment loss 2.Moderate periodontal destruction at least, in 2 interproximal sites in each quadrant. 3.Minimum presence of 4 permanent teeth per quadrant (excluding 3rd molars)

Exclusion criteria

Exclusion criteria: 1.Sites with pseudo pockets / advanced periodontal destruction with mobility and Grade IV furcation involvement 2.Periodontal therapy within last 6 months 3.Previous history of intake of antibiotics over last 6 months 4.Systemic condition / disease, having influence on course and treatment outcomes of periodontal disease. 5.Screening for the infectious disease will be done and the subjects with infectious diseases will be excluded. 6.Individuals with known platelet disorders 7.Smokers.

Design outcomes

Primary

MeasureTime frame
To assess the changes in Clinical attachment level (CAL) before and after therapy within and between the groups.Timepoint: Baseline, 3 months, 6 months—

Secondary

MeasureTime frame
To assess the changes in Probing pocket depth (PPD) before and after therapyTimepoint: Baseline, 3 months, 6 months—

Countries

India

Contacts

Public ContactDr Anupama Tadepalli

SRM dental college

anupamamds@gmail.com9677065517

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026