Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: intravenous infusion of lignocaine: Effect of lignocaine infusion of 1.5mg/kg loading dose followed by intravenous infusion of 1.5 mg/kg/hr lignocaine prepared in a volume of 20ml/hr fo
Sponsors
Amulya Kodkani
Eligibility
Inclusion criteria
Inclusion criteria: American College of Anaesthesiologists(ASA) physical status grade 1
Exclusion criteria
Exclusion criteria: 1.Revision Total Knee Replacement 2.Contraindications to spinal anaesthesia or previous failed spinal anaesthesia 3.Allergy to lidocaine 4.History of long standing diabetes mellitus,cardiac or neurological disease 5.Impaired Renal or Hepatic Function 6.Psychiatric illness affecting pain perception e.g severe depression,anxiety disorder 7.chronic Pain,other than chronic knee pain 8.Alcohol or substance abuse,regular use of strong opiods 9.Patients with obesity,anticipated difficult airway 10.Pregnant patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of sensory block after spinal anaesthesiaTimepoint: T1-time to loss of pinprick at T10 dermatome T2-Time to achieve highest level of sensory block T3-Time to recovery of sensory block | — |
Secondary
| Measure | Time frame |
|---|---|
| total requirement of analgesia in first 24 hours after surgeryTimepoint: in the first 24 hours postoperatively;anaesthesiologist rating the quality of anaesthesiaTimepoint: after completion of the surgery;bispectoral index (BIS)Timepoint: every 5 mins throughout the surgical procedure;duration of motor block after spinal anaesthesiaTimepoint: from administration of spinal drug to the return of bromage scale score to 0;INTRAOPERATIVE HEMODYNAMICS -HR,SBP,DBP and MAPTimepoint: every 5 mins throughout the surgical procedure;onset of motor blockTimepoint: from administration of spinal drug to modified bromage scale score of 3;onset of sensory blockTimepoint: from administration of spinal drug upto absence of pin prick at the T10 dermatome;postoperative VAS scoreTimepoint: at 4,8,12 and 24 hours postoperatively;surgeons rating of quality of operative conditionsTimepoint: after completion of the surgery;time for first postoperative analgesic requestTimepoint: postoperative period;total intraoperative sedation ( midazolam ) requiredTimepoint: to achieve a Ramsay Sedation Score of 3 during the surgical procedure | — |
Countries
India
Contacts
Public ContactAnju R Bhalotra
Maulana Azad Medical College
Outcome results
None listed