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A comparative study on the effect of Fentanyl (pain medication used in general anaesthesia) on the dose requirements of propofol (common drug used in general anesthesia using clinical monitors .

The influence of Fentanyl on the effect site concentration of propofol during induction of anaesthesia using clinical assessment score and bispectral index

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/12/038532
Enrollment
60
Registered
2021-12-09
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

None listed

Sponsors

Anu David
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Elective surgery under general anaesthesia Physical Status-ASA Class I and II

Exclusion criteria

Exclusion criteria: Subjects who are allergic to propofol and fentanyl,history of Diabetes Mellitus, Coronary Artery Disease, Hypertension,pregnant women, any known neurological disorder,on psychotropic drugs , deaf and dumb, difficult intubation, BMI >35 for females and >40 for males

Design outcomes

Primary

MeasureTime frame
To determine whether Fentanyl would significantly reduce the effect site concentration of propofol required to abolish response to verbal commands or loss of response to noxious stimulusTimepoint: 2 months—

Secondary

MeasureTime frame
To determine relation between effect site concentration of propofol and objective end point of sedation (Bispectral index of 60)during propofol anaesthesia with or without FentanylTimepoint: 2 months—

Countries

India

Contacts

Public ContactDrBinu Puthur Simon

Amala Institute of Medical Sciences

binupsimon@yahoo.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026