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General Anesthesia intubation response

Effect of oral clonidine and oral tizanidine on the induction dose of propofol and intubation response in general anesthesia-comparative study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/12/038529
Enrollment
100
Registered
2021-12-09
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: drug clonidine: 100mcg of clonidine were adminstered 60 min before the induction of general anesthesia and will be monitoring the intubation 00,1,3,5 min response at the time of intubat

Sponsors

self
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: willing patients,ASA1 &2 ,ELECTIVE CASES

Exclusion criteria

Exclusion criteria: ASA 3 OR MORE PREGNANT AND LACTATING MOTHER ANTICIPATED DIFFICULT AIRWAYUNCONTROLLED CHRONIC ILLNESS LIKE DIABETES MELLITUS,ASTHMA,SMOKERS,ON MONOAMINA OXIDASE INHIBITORS,PATIENTS WITH PREVIOUS RENAL AND HEPATIC DYSFUNCTION,HEAR DISEASES,VALVULAR HEART DISEASE,ELECTROPHYSICAL ABNORMALITIES,AND OTHER HEMODYNAMIC INSTABILITY.

Design outcomes

Primary

MeasureTime frame
This study attempts to survey the effects of the oral premedication Tizanidine and clonidine on intraoperative hemodynamic responses during tracheal intubationTimepoint: at intubation,1,3 abd 5 min after intubation—

Secondary

MeasureTime frame
calculation the induction dose of propofol in general anesthesia.Timepoint: 30min—

Countries

India

Contacts

Public ContactElavanya

srilakshmi narayana institute of medical sciences

dr.lavanya08@gmail.com9629181969

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026