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Correlation of End-Tidal Carbon dioxide (ETCO2, a ventilatory parameter) with Cardiac output in the assessment of fluid responsiveness: A Prospective Observational Study

Correlation of End-Tidal Carbon dioxide with Left Ventricular Outflow Tract derived Cardiac Output in the assessment of fluid responsiveness: A Prospective Observational Study - ETCO2 vs CO

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2021/12/038508
Enrollment
50
Registered
2021-12-08
Start date
Unknown
Completion date
Unknown
Last updated
2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: After induction of General Anesthesia, a fluid bolus of 250 mL 0.9% Saline is infused over 10 minutes.: After induction of General Anesthesia, first set of measurements will be obtained

Sponsors

Nil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anaesthesiologists (ASA) Grade I and II patients undergoing lower abdominal or lower limb surgeries in supine position under General Anesthesia, with requirement of fluid bolus for volume expansion.

Exclusion criteria

Exclusion criteria: 1. Patient refusal. 2. Pregnant patients. 3. Fluid overload before anesthesia. 4. Patients undergoing laparoscopic surgery. 5. Patients with heart failure. 6. Patients with no available doppler acoustic window.

Design outcomes

Primary

MeasureTime frame
End-Tidal Carbon dioxide (ETCO2) and Cardiac output (CO)Timepoint: 1. After induction of general anesthesia. 2. 1 minute after administering a fluid bolus of 250 mL Saline over 10 minutes.—

Secondary

MeasureTime frame
Fluid responsiveness after giving fluid bolus during surgeryTimepoint: Intra-operative baseline values of EtCO2 and cardiac output will be measured 10 min after induction and fluid bolus of 250ml NS will be given over 10 minutes,EtCO2 and cardiac output will be measured again,10 minutes and 30 minutes after induction .—

Countries

India

Contacts

Public ContactDr D K Tripathy

All India Institute of Medical Sciences Rishikesh

drdebendra@gmail.com9443278806

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026