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Comparison of two drugs adding with bupivacaine in spinal anaesthesia for pain relief in Legs(lower limb orthopaedic) operation

â??Nalbuphine versus Magnesium Sulfate as adjuvant to intrathecal 0.5% hyperbaric bupivacaine in lower limb orthopaedic surgery - A prospective randomised double blind comparative studyâ??

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/12/038489
Enrollment
60
Registered
2021-12-07
Start date
Unknown
Completion date
Unknown
Last updated
2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S720- Fracture of head and neck of femur Health Condition 2: S724- Fracture of lower end of femur Health Condition 3: S823- Fracture of lower end of tibia Health Condition 4: S825- Fracture of medial malleolus Health Condition 5: S820- Fracture of patella Health Condition 6: S723- Fracture of shaft of femur Health Condition 7: S824- Fracture of shaft of fibula Health Condition 8: S822- Fracture of shaft of tibia Health Condition 9: S821- Fracture of upper end of tibia Health

Interventions

Intervention1: Intrathecal nalbuphine versus magnesium sulphate as an adjuvant with bupivacaine: â??Nalbuphine versus Magnesium Sulfate as adjuvant to intrathecal 0.5% hyperbaric bupivacaine in lower

Sponsors

Department of Anaesthesiology
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with ASA physical status Grade I and II of either sex. Patients in the age group of 18-60 years. Posted for lower limb orthopaedic surgeries under spinal anaesthesia.

Exclusion criteria

Exclusion criteria: Patients posted for emergency surgeries. Pregnant patients. Patients having coagulation abnormalities, platelet count 1.5, or on anticoagulants.

Design outcomes

Primary

MeasureTime frame
Duration of AnalgesiaTimepoint: 24 hours post operatively—

Secondary

MeasureTime frame
Onset and duration of sensory block Onset and duration of motor block HaemodynamicsTimepoint: Intraoperative(3 hours)—

Countries

India

Contacts

Public ContactAshish Sharma

RNT Medical College udaipur

sharma0979@yahoo.co.in9214323557

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026