Health Condition 1: O- Medical and Surgical Health Condition 2: O- Medical and Surgical Health Condition 3: M518- Other thoracic, thoracolumbar andlumbosacral intervertebral disc disorders
Conditions
Interventions
Intervention1: pre emptive analgesia: pre emptive paracetamol 1 gm each given orally at mid night and 1 hr before lumbar laminectomy .
Control Intervention1: pre emptive analgesia: pre emptive Inj. di
Sponsors
Department of AnaesthesiaSNMedical College Intramural funds
Eligibility
Inclusion criteria
Inclusion criteria: 1. ASA physical status 1 and 2. 2. Age 18-70 yrs. 3. Body mass index less than 30 kg/m2. 4. Patients undergoing elective lumbar spine surgeries.
Exclusion criteria
Exclusion criteria: 1.Patient refusal to give consent 2.Co-morbidities like Anaemia , DM , HTN, arthritis. 3.Moderate or severe renal impairment ( serum creatinine >=1.6 mg/dl) 4.Known asthmatic patient. 5.Opioids or other drug abuse. 6.Use of NSAIDs or Paracetamol in 24 hr prior to surgery. 7.Participants with known allergy to study groups
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pre - emptive combination of paracetamol-diclofenac, paracetamol-tramadol may reduce the total need for analgesic consumption and may prolong the time to first analgesia request when compared to paracetamol group.Timepoint: The NRS score will be recorded at recovery room when patient is fully awake from anaesthesia at 1,2,4,8,12 and 24 hrs. | — |
Secondary
| Measure | Time frame |
|---|---|
| Pre-emptive combination of Paracetamol-Diclofenac and Pracetamol-Tramadol may reduce the total Tramadol consumption and prolongs the time to 1st analgesia request compared to Paracetamol alone. Timepoint: The NRS score will be recorded at recovery after the patient is fully awake from anaesthesia, at the end of 1,2,4,8,12 and 24 hr. | — |
Countries
India
Contacts
Public ContactDr Priyanka N Gouda
S N Medical College, BAGALKOT
Outcome results
None listed