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Comparison Of Zinc And Benzocaine (local anesthetic) Lozenges For Prevention Of Sorethroat that can occur after surgery

Comparison Of Zinc And Benzocaine Lozenges For Prevention Of Post Operative Sorethroat : A Prospective Randomised Comparative Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2021/12/038461
Enrollment
183
Registered
2021-12-06
Start date
Unknown
Completion date
Unknown
Last updated
2022-02-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: administration of lozenges to prevent post operative sore throat: based on randomisation, patients will be administered either zinc or benzocaine lozenges, 30 minutes before induction o

Sponsors

A CHAITANYA PRATYUSHA
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anaesthesiologists Physical Status (ASA-PS) I and II General anesthesia with endotracheal tube Duration of surgery greater than 1 hour and less than 3 hours duration.

Exclusion criteria

Exclusion criteria: Patients with a recent history of sore throat or upper respiratory tract infection Difficult airway Smokers Pregnant patients Patients with allergy to either zinc or benzocaiaine

Design outcomes

Primary

MeasureTime frame
Incidence of post operative sore throat within first 24 hours after extubation. The severity of Post operative sore throat will be graded on a 4-point scale ranging from 0 to 3; 0 being no sore throat, 1 being mild discomfort (complaints only upon questioning), 2 being moderate sore throat (complains of his/her own), and 3 being severe sore throat (change in voice, hoarseness and throat pain). Timepoint: Incidence of post operative sore throat within first 24 hours after extubation. The severity of Post operative sore throat will be graded on a 4-point scale ranging from 0 to 3; 0 being no sore throat, 1 being mild discomfort (complaints only upon questioning), 2 being moderate sore throat (complains of his/her own), and 3 being severe sore throat (change in voice, hoarseness and throat pain).—

Secondary

MeasureTime frame
1. Time of onset of postoperative sorethroat 2. Incidence of sorethroat at 1 hour, 2 hours, 3 hours, 6 hours, 12 hours and 24 hours 3. Side effects such as nausea, vomiting, metallic taste, and diarrhea. Timepoint: post operative sore throat assessed at 1 hour, 2 hours, 3 hours, 6 hours, 12 hours and 24 hours—

Countries

India

Contacts

Public ContactA CHAITANYA PRATYUSHA

ESIC MEDICAL COLLEGE HOSPITAL

gopi59@hotmail.com9490295031

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026