Health Condition 1: H301- Disseminated chorioretinal inflammation
Conditions
Interventions
Intervention1: Intravitreal dexamethasone implant (Ozurdex):
Depot intravitreal preloaded injectable implant
Control Intervention1: Intravitreal dexamethasone injection: Single use, reconstituted dex
Sponsors
LV Prasad Eye Institute
Eligibility
Inclusion criteria
Inclusion criteria: 1. Clinical signs and/or symptoms of endophthalmitis with special reference to four ocular tissues (cornea, anterior chamber, iris, and vitreous; Table 1); post-operative or post trauma endophthalmitis within 6 weeks of the diagnosis. 2. Visual acuity from 3. Culture positive endophthalmitis 4. Definite clinical evidence of no worsening after first two antibiotic injections
Exclusion criteria
Exclusion criteria: 1. Culture negative endophthalmitis 2. Chronic/delayed-onset endophthalmitis 3. h/o glaucoma 4. h/o previous documented steroid response
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Number of days required to reach the defined end point of treatment 2. Total number of OPD and OR visits Timepoint: Day 0, 1, 4, 7, 14, 30, 45 | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Visual acuity gain 2. IOP 3. Macular thickness and perfusion on OCTA Timepoint: Day 0, 1, 4, 7, 14, 30, 45 | — |
Countries
India
Contacts
Public ContactDrVivek Pravin Dave
L V Prasad Eye Institute
Outcome results
None listed