Health Condition 1: D508- Other iron deficiency anemias
Conditions
Interventions
Intervention1: Ferrous sulphate 200mg tablet containing 60mg of elemental iron: Ferrous sulphate 400mg tablets, containing 120mg of elemental iron (2 x 200mg tablets given together) given as single do
Sponsors
Jawaharlal Institute of Postgraduate Medical Education and Research
Eligibility
Inclusion criteria
Inclusion criteria: Newly diagnosed iron deficiency anaemia patients, with haemoglobin concentration between 6-10 g/dl, with peripheral blood smear suggestive of iron deficiency anemia and with serum ferritin level <30 mcg/l
Exclusion criteria
Exclusion criteria: 1. Pregnant and lactating women 2. Already diagnosed to have iron deficiency anemia and on treatment 3. Known coronary artery disease/chronic heart failure 4. History of overt gastrointestinal bleeding (haematemesis/ melena) 5. Chronic kidney disease (serum creatinine >2 mg/dl) 6. Known malabsorption 7. Heavy alcohol abuse (alcohol intake >once/week) 8. Dimorphic anaemias 9. History of peptic ulcer disease on long term acid suppressive therapy 10. Known anaemia of chronic disease (SLE/rheumatoid arthritis/HIV infection/ Tuberculosis)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the quantum of haemoglobin increment in once daily and alternate day oral iron replacement arms on Day-28Timepoint: To assess the quantum of haemoglobin increament in once daily and alternate day oral iron replacement on Days-14 and 28 | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.To study the effect of oral iron replacement on serum hepcidin levels in the two arms at baseline and on Day-14 2.To determine frequency of adverse events and compliance with therapy in the two arms 3.To assess the increment in haemoglobin concentration in the two arms on Day-56Timepoint: Day-0 (Start of intervention), Day-7,Day-14,Day-28,Day-42 and Day-56 | — |
Countries
India
Contacts
Public ContactDr Vinod K V
JIPMER, Pondicherry-06
Outcome results
None listed