Health Condition 1: R270- Ataxia, unspecified Health Condition 2: G20- Parkinsons disease
Conditions
Interventions
Intervention1: repetetive Transcranial Magnetic Stimulation: PD 2000 pulses of 5Hz at Primary Motor Area.
SCA2 2000 pulses of 1 HZ at Cerebellum(vermis).
SCA 12 2000 pulses of 1 Hz at Cerebellum
Con
Sponsors
DST
Eligibility
Inclusion criteria
Inclusion criteria: FOR PD- Diagnosis of PD, based on UK brain bank criteria for diagnosis of PD. Hoehn and Yahr stage from 1 to3. On stable dopaminergic drugs for at least 30 days FOR SCA- Genetically confirmed SCA-2 and SCA-12. Subjects 30 and above on stable medication for at least 30 days.
Exclusion criteria
Exclusion criteria: Features suggestive of other causes of Parkinsonism or Parkinson plus syndrome. Subjects with neuropsychiatric co-morbidity Subjects with hypertension or diabetes would be excluded if uncontrolled on drugs. Subjects with pregnancy. Subjects with any orthopedic illness (arthitis etc.)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Gait questionnaire. 2. Clinical gait examination 3. UPDRS Motor Score for PD 4. Posture / gait and Kinetic function sub segments of ICARS 5. Gait and stance sub segments of SARA 6. Assessment with device 7. Resting state Functional MRITimepoint: Day 1 Day 5 | — |
Secondary
| Measure | Time frame |
|---|---|
| 6. Assessment with device 7. Resting state Functional MRITimepoint: Day 1 Day 5 | — |
Countries
India
Contacts
Public ContactDeepak Joshi
IIT Delhi
Outcome results
None listed