Health Condition 1: G973- Intraoperative hemorrhage and hematoma of a nervous system organ or structure complicating a procedure
Conditions
Interventions
Intervention1: Remote ischemic preconditioning Group: In group P we will inflate the upper extremity blood pressure cuff thrice for 5 min to 30 mmHg above the systolic blood pressure with 5 min interv
Sponsors
SKIMS SOURA
Eligibility
Inclusion criteria
Inclusion criteria: Middle cerebral artery aneurysm with subarachnoid hemorrhage. All age groups Consent for surgical management of ruptured aneurysm. Consent for participation in the study
Exclusion criteria
Exclusion criteria: Upper limb cellulitis or peripheral vascular disease. Refusal for consent. Unruptured aneurysm. Endovascular coiling or conservative treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Compare the fresh onset neurological deficit between control and study group 2. To compare the post extubation GCS between the control and study group 3.To compare the levels of ischemic biomarkers(Neuron specific enolase and S 100 Beta )Timepoint: GCS and neurodeficit one day prior to surgery, 24-36 hours after surgery gcs and neurodeficit monitoring daily monitoring biomarkers on day prior to surgery , 24-36 hours after surgery and 7 day after surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| vasospasm as identified by TCDTimepoint: Before surgery every day post operative till discharge | — |
Countries
India
Contacts
Public ContactAymen Masood
SKIMS SOURA
Outcome results
None listed